See section Vacancies https://cme.webs.uvigo.es/vacancies/
We found that several evolutionary and environmental processes affected the current (east-west) Asian genetic gradient of modern humans. Published in Molecular Ecology, https://onlinelibrary.wiley.com/doi/abs/10.1111/mec.15479
We found that ignoring the variation of codon frequencies among sites biases the estimation of molecular adaptation (dN/dS). Published in Bioinformatics, https://academic.oup.com/bioinformatics/article-abstract/36/2/430/5532222?redirectedFrom=fulltext
We developed a new version of our program “ProtASR” to infer ancestral sequences of proteins accounting for the protein folding stability. A methodology that produces more realistic ancestral sequences respect to those obtained using traditional empirical substitution models. This study was done in collaboration with Ugo Bastolla (Center for Molecular Biology Severo Ochoa). Just published in Methods in Ecology and Evolution, https://besjournals.onlinelibrary.wiley.com/doi/abs/10.1111/2041-210X.13341
We investigated the peopling of the Philippines by modern humans, including the estimation of evolutionary parameters and migration patterns such as migration corridors connecting the continent with the archipelago and the presence of long-distance dispersal. This study was done in collaboration with the lab of Antonio González-Martín (University Complutense of Madrid). Just published in Scientific Reports,
David Ferreiro and Marina Kanellou (Greece) just arrived the lab to perform reseach on population genetics and evolution of modern humans. Welcome to the lab!
We obtained a Grant from the “Fundación BBVA” to study human evolution in the Iberian Peninsula.
We presented nice communications on molecular adaptation, protein evolution and human evolution!
CME Lab at the SMBE 2019. Left to right: Roberto Del Amparo, Catarina Branco and Miguel Arenas.
The genetic gradient of modern humans of the Americas present a northwest-southeast direction along the entire continent. However at regional levels the genetic gradient can present directions directions as a consequence of population and environmental processes. Just published in Heredity,
The Neolithic expansion at both shores of the Mediterranean Sea was not different after all. A nice study applying approximation Bayesian computation for model selection and parameters estimation. Just published in Molecular Biology and Evolution,